Dr. Saber’s Blog

Rejuvenation Takes Huge Leap Forward: Making Skin Cells Younger

Dr. Saber – an expert in using super-skilled plastic surgery to help her patients achieve rejuvenation — may one day be able to actually make you younger. Someday we may have the technology to actually de-age your cells.

Imagine. “Doctor, can you please smooth out my wrinkle lines and make my skin 30 years younger?”

If you’re thinking this entire idea has Buck Rogers written all over it, read on!

Rejuvenating Skin Cells

The proof is in the study

Though still several years in the future, a recent study in the UK demonstrated how a person’s cells can be modified to go back in time.

To be sure, other studies have taken baby steps over the last decade to pare the aging of respondents. But this is the first time that the clock has been turned back a whopping 30 years (technically called de-aging).

Here’s how they found youth

First, researchers selected three middle-aged donors (average age 50 years) and three volunteers between the ages of 20 and 22. They then took skin cells from the middle-aged donors and de-aged them in the lab (officially called “maturation phase transient reprogramming”). When these de-aged skin cells were compared to samples taken from the younger volunteers, they were chemically and genetically similar.

As a bonus — the research team noticed the de-aging technique had also affected genes related to age-related diseases such as Alzheimer’s and cataracts.

It took only 13 days to take the cells back in time (much faster than a previous study by Shinya Yamanaka that took 50 days for a cellular change). However, the previous study reverted skin cells back into stem cells. In the UK study, the cells retained their identity as skin cells.

Because the cells maintained their identity, they also acted like younger skin cells. When injured, the de-aged cells quickly moved to heal the wound — just like younger cells.

But don’t begin cheering just yet. “We have proved that cells can be rejuvenated without losing their function and that rejuvenation looks to restore some function to old cells,” said the study’s lead researcher in Live Science. But this fantastic experiment is not ready for prime time yet. For now, it’s just an interesting experiment.

Here’s what’s missing

The scientists are left wondering how fibroblasts (skin cells) from younger or older individuals would react to the new reprogramming method. Would cells from people of very different ages always de-age by 30 years?

In addition, there is currently no way of knowing how the reprogrammed cells might react inside a living organism. The previous study — which reverted skin cells into stem cells — carried a risk of the completely reprogrammed cells becoming cancerous. These new de-aged skin cells could carry the same risk.

Illustration of young and aged skin components.

What the future may hold

Even though there is no immediate plan to introduce the cells into the mainstream, this is still a great step forward for science. Continued research could pin down which genes can rejuvenate cells without reprogramming. We could someday be able to reduce the effects of aging in more than just the skin.

Why choose Saber Plastic Surgery for your rejuvenation procedures?

Dr. Sepideh Saber’s, MD, FACS, approach to cosmetic surgery combines extensive experience and an empathetic female perspective. This helps her understand the unique needs and anxieties of each patient.

She is a Stanford University-trained board-certified plastic surgeon who has completed residencies at the University of Southern California and New York University. Using cosmetic surgery and injectables Dr. Saber can help take years off your appearance — no sci-fi cell reprogramming required.

Patients from all walks of life have found her a valuable ally for their health and self-esteem. She provides various procedures such as rhinoplasties, breast augmentations or reductions, and facelifts. She can also help patients remove old fillers or help them tailor a plan to improve their skin elasticity

To request a consultation, call (877) 205-4100 or schedule a consultation online.

We serve patients in Encino, Woodland Hills, Sherman Oaks, Calabasas, Burbank, Glendale, Hidden Hills, Agoura Hills, Northridge, North Hollywood, Malibu, Topanga, Canoga Park, Reseda, Valley Glen, Chatsworth, West Hills, Winnetka, Universal City, Bel Air, Beverly Hills, Downtown Los Angeles, Silverlake, and Echo Park.

Dr. Saber graduated from Stanford University’s world-renowned medical school and did her plastic and reconstructive surgery residency at the equally lauded University of Southern California. She then completed a fellowship at New York University in the extremely challenging and delicate disciplines of hand surgery and microsurgery.

Dr. Saber offers a more sensitive, female perspective for patients of all ages, genders, and orientations. Former patients from all walks of life have praised not only their treatment outcomes but her caring, thoughtful approach to a wide array of appearance and health-related matters.
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    Dr. Sepideh Saber, MD, FACS

    👩🏻‍⚕️ Board Certified Plastic Surgeon
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  • What patients say about Dr. Saber

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    I was fortunate to find Dr. Saber after researching board-certified surgeons who specialize in breast cancer reconstruction revision surgery. I knew I was in good hands from the moment I spoke with the lovely and efficient Marlene, Dr Saber's office manager. Dr Saber patiently listened to my concerns and, after examining me, explained what I could realistically expect the outcome to be from another surgery. She also explained to me that she would need to review my previous surgery notes before we could discuss a possible further surgery, which I found comforting and highly ethical. I also discussed a couple of other procedures that I would like done, including fat removal from my large upper arms that had caused me great embarrassment for several years. Dr. Saber is an excellent surgeon who is incredibly kind and genuine. She truly understands the female body and the emotional aspect of body insecurities yet, she is transparent about what can and cannot be done and takes time to discuss realistic expectations and outcomes. My breast reconstruction revision surgery will take place in the New Year, but in the meantime, I have the most fabulous upper arms that I recently flaunted in a strapless dress (something I have not done in years). Dr Saber is truly one of a kind, and I still cannot believe how fortunate I am to have found her. I highly recommend Dr Saber.

    Linda DeCarlo November 29, 2023

    I don’t have enough wonderful words to describe Dr Saber and Marlene! I had a tummy tuck done this year and from start to finish the entire experience was amazing. Marlene is always so helpful and works so hard to make every detail a breeze for you. When I had my consultation with Dr Saber I was at a point of complete agony with my body. She instantly took that stress and frustration off my shoulders! As a woman not being heard by doctors for years I left that consultation with happy tears knowing I had finally found my Dr. It was a major surgery and I felt completely zen and at peace going in because she really does make you feel that safe. I didn’t think I would ever look the way I do now! She gave me the gift of having the body I kept fighting for. I will never stop recommending her.

    Monica Prusa October 9, 2023

    I saw Dr. Saber when I broke my wrist. I ended up having to have surgery. She did an excellent job and I am healing nicely. She was very professional, but was also very kind and compassionate. I would highly recommend her!!

    Sandy Schaupp September 13, 2022

    I LOVED DR SABER!!! There are a few reasons why I chose her. One was because she’s a female Doctor that was my goal who also did a good job (which I was able to confirm with all her before and after photos) and what sold me was my safety in mind. She made me feel like I was in the best hands ever along with Marlene who coordinated everything THANK YOU LADIES! Dr Saber helped me get back the body I have always desired. I had a lot of stomach fat from weight gain and I lost weight so a lot of my weight was in my front lower and upper abdomen. Now I have a super beautiful curvy body like an hourglass after a tummy tuck and lipo she did. She understood the assignment hahaha . I’m 32 years old no kids just wanted to enjoy my younger body looking and feeling beautiful and she really took good care of me. Even after hours I had an emergency due to my fault but she was there and got back to me very quickly and I’m very grateful. I also think her work says a lot because I stopped taking pain medication on the 3rd day after surgery and was fine with very minimal pain I was able to tolerate the healing process. Highly recommend going with her I just had a wonderful experience and would do it all over again if I had too. Maybe after I have kids. Thanks Dr Saber and team <3

    STEPHANIE d July 15, 2022

    Dr.Saber is by far one of the best plastic surgeons. I love how she takes her time to explain any procedure to the patients understanding. She always makes sure to answers any and all questions.From fillers to body contours she’s the one you want.

    Katherine Melara February 15, 2022

    Dr Saber is amazing! She is caring and very informative. I went in for fillers and she explained procedure step by step. I highly recommend her and look forward to future visits.

    Amanda Vazquez December 18, 2020

    Dr. Saber was friendly, knowledgeable and professional. She took time to listen, answer all my questions and was forthright in her recommendations. Her staff was friendly and helpful. I was very happy with the results and plan on going back. If you are looking for a first rate professional experience look no further she is the doctor for you!

    T R December 18, 2020

    Dr. Saber is one of a kind plastic surgeon with a heart of gold. She is a well verse plastic surgeon that puts her patient's needs before anything else. She genuinely cares about every single patient, and her work speaks for itself. I notice every post-operative result on her Instagram (@saberplasticsurgery) the patients have this glow that radiates through. I have been going to Dr. Saber for my Botox for the past 3 years, and love the results every time. I know who I will be going to for any future plastic surgery needs, and will confidently refer family and friends to Dr. Saber for any Botox, fillers, and plastic surgery consultations.

    Rudy Garcia December 16, 2020

    I have nothing but great things to say about Dr. Saber! I am so pleased with my results from a breast augmentation she performed on me back in late June! She answered all my questions and concerns before and after my surgery. She’s very easy to get in contact with and she’s so nice. She made feel so comfortable throughout the whole process. 100/10 Lover her work!!

    Amanda Villegas October 15, 2020

    Dr Saber is hands down the best surgeon! She took her time answering my questions and explained procedure in detail. After doing liposuction six months ago, I am extremely happy with my results and I appreciate her so much.

    Marlene Cosentino October 15, 2020

    Dr. Saber is so kind and thorough with her patients! She is an amazing doctor and genuinely cars about everyone she comes in contact with. I would recommend her to anyone for any hand surgery or cosmetic procedure.

    Rachel Meach October 15, 2020