Dr. Saber’s Blog
When transgender men and transmasculine individuals begin their gender transitioning journey, one of the most important conversations they’ll have with healthcare professionals involves fertility preservation. It’s essential to think about keeping your options open for biological children in the future, even as you pursue gender-affirming treatments that align with your gender identity.
Let’s break down why this matters and what options are available, because understanding your reproductive health choices is part of comprehensive transgender healthcare.

Testosterone therapy and gender-affirming surgeries can significantly impact your ability to have biological children later on. While this might not be on your mind right now, it’s something worth considering before you start hormone replacement therapy (HRT) or undergo procedures like top surgery or hysterectomy.
When trans men begin testosterone therapy, it affects their menstrual cycle and ovulation. Many people find that their menstruation stops entirely, which can be a huge relief for those experiencing gender dysphoria around their reproductive organs. However, testosterone can cause changes in the ovaries that might impact future fertility.
The good news is that some research suggests that fertility may return after stopping hormone therapy, if that’s a decision you want to make to pursue biological children. However, there’s still a risk of permanent changes. That’s why healthcare providers increasingly recommend discussing fertility preservation methods before starting HRT.
Female-to-male gender affirming surgeries, like hysterectomy (removing the uterus) or oophorectomy (removing the ovaries), typically result in permanent infertility. While these procedures can be life-changing for mental health and overall well-being, they do close the door on carrying biological children.
The field of assisted reproductive technology (ART) has come a long way, and there are several options for fertility preservation. Many of these options are the same as those used for cisgender women who are undergoing radiation or another health concern that could affect their fertility. Still, they are also applicable to transgender individuals, including trans men and nonbinary people assigned female at birth.
This is probably the option most people are familiar with. The process involves:
The eggs can later be used with a partner’s sperm, donor sperm, or with a gestational carrier. Many trans men choose this option because it preserves their genetic material without requiring a partner at the time of preservation.
If you have a partner or choose to use donor sperm, embryo freezing might be an option. This involves fertilizing retrieved eggs to create embryos, which are then frozen. Statistics show embryos have higher success rates than frozen eggs alone, but this option requires making decisions about a sperm source upfront.
This newer technique involves surgically removing and freezing a portion of ovarian tissue. It’s beneficial for transgender men who want to start testosterone therapy before puberty or reproductive maturation. Unlike other methods, it doesn’t require hormone stimulation, but it’s still considered experimental in many places.

While these fertility preservation procedures may seem straightforward, that’s not always the case, especially for transgender people navigating an already complex healthcare system.
Many trans men experience conflicting feelings about fertility preservation. Since the procedures focus on reproductive organs, they can trigger or exacerbate gender dysphoria. There’s often tension between wanting to start testosterone therapy immediately and taking time for fertility preservation.
This is where working with healthcare providers experienced in transgender healthcare becomes essential, as compassionate physical and mental health support during this process is imperative. You want to choose someone, such as Dr. Sepideh Saber, who always remains sensitive to the needs of each patient and their mental and physical well-being.
Finding knowledgeable healthcare professionals can be challenging. Not all reproductive endocrinologists or gynecology practices have experience with transgender patients. Some trans men end up traveling to access appropriate care. This can add financial and emotional stress.
Insurance coverage is another major hurdle. Most insurance plans don’t cover fertility preservation for transgender individuals. As a result, these procedures become financially challenging for many people.
Here’s something many people don’t realize: even on testosterone therapy, pregnancy can still occur. Healthcare providers emphasize that trans men who are sexually active with partners who produce sperm should consider birth control options. This is because breakthrough ovulation is possible, resulting in a fertilized egg and subsequent pregnancy.
It is worth mentioning that some trans people do become pregnant and give birth. Pregnant trans men face unique challenges in obstetrics care. For example, finding supportive healthcare providers and navigating everything from prenatal care to decisions about c-section delivery.
The experience of chestfeeding (the term many trans men prefer over breastfeeding) and lactation support requires healthcare professionals who understand both transgender healthcare needs and postpartum care. This is an evolving area where more education is needed across medical specialties.
Family building looks different for everyone. That’s especially true in the LGBTQ+ community. Some transgender individuals pursue biological children through fertility preservation and IVF. Others choose adoption or donor gametes. Some decide not to have children at all.
The key is having options and making informed decisions that align with your gender identity, life goals, and mental health needs. If possible, this should be done before pursuing gender affirmation procedures. But whether you’re just starting to consider hormone therapy or you’re years into your gender affirming transition, it’s never too late to have conversations about reproductive health with knowledgeable healthcare providers.
If you’re considering fertility preservation, look for medical professionals who:
Remember, this decision is deeply personal. There’s no right or wrong choice – only what’s right for you, your gender identity, your mental health, and your future family planning goals.
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Dr. Sepideh Saber is a renowned plastic surgeon based in Los Angeles. She specializes in gender-affirming surgeries and cosmetic procedures. She believes in empowering her patients through knowledge, empathy, and expert care.
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Unfortunately, no. Testosterone suppresses egg maturation, so you’ll need to stop hormone therapy and allow your menstrual cycle to return before egg freezing. This process typically takes a few months. Many trans men find this challenging due to the return of menstruation and potential gender dysphoria.
The timeline varies, but most healthcare providers recommend stopping testosterone therapy for 2-4 months before starting the egg retrieval process. Your reproductive endocrinologist will monitor your hormone levels and menstrual cycle to determine the right timing.
No, trans men assigned female at birth cannot produce sperm, as this requires the genital structures, namely testes, to be able to do so. However, there are many paths to biological children through egg preservation, and various family building options including donor sperm, adoption, and surrogacy.
Transgender men can become pregnant through sexual intercourse with biological men, even during hormone replacement therapy, but not after gender affirming surgeries like hysterectomy or oopherectomy.
Yes, breakthrough ovulation can occur even while on testosterone therapy. Healthcare professionals recommend that sexually active trans men who could become pregnant use contraception if they don’t want to conceive.
Nonbinary people assigned female at birth have the same fertility preservation options as trans men and cis women. The key is working with healthcare providers who respect your gender identity while providing comprehensive reproductive health care.
This varies for each person. Some transgender individuals choose to preserve fertility before starting any hormone therapy or gender surgery, while others may pause their medical transition temporarily. We recommend discussing your priorities and timeline with both your gender-affirming care provider and reproductive health specialist.
Reproductive wish in transsexual men
https://doi.org/10.1093/humrep/der406
Fertility preservation in the transgender patient: expanding oncofertility care beyond cancer
https://doi.org/10.3109/09513590.2014.920005
Fertility preservation for transgender children and young people in paediatric healthcare: a systematic review of ethical considerations
https://pubmed.ncbi.nlm.nih.gov/34980674/
Considerations in genetic counseling of transgender patients: Cultural competencies and altered disease risk profiles
https://pubmed.ncbi.nlm.nih.gov/33368789/
Fertility preservation counseling needed for transgender men
https://medicalxpress.com/news/2022-09-fertility-transgender-men.html